Formulations Moisture
There is no doubt we live in a fast-paced society that does not show any signs of slowing down any time soon. To relieve some of the stress associated with always being on the go, many people have turned to online to find ways of pampering themselve and looking good. Here at A Woman"s Place Too.com we offer a variety of skin care services, which are listed above. Use this list to help you determine what products you may be interested in. We bring you the latest break throughs in skin care technology at an affordable price. We are committed to helping you improve and maintain skin wellness. Our focus is on anti-aging treatments and looking younger and more beautiful without surgery. Specialty products include laser hair removal, microderm abrasion, Acne Blemish Control, Aromatherapy, Cellulite Treatments, Massage items, Anti-Aging Products, and finally Scar & Stretch mark Reduction. We hope you enjoy our treatments and enjoy shopping!
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3 Cold-Hard Facts About Facial Moisturizers
What goes through your mind when you're shopping for facial moisturizers? Brand-name recognition? Price? Endorsements? Scent? If it is any of these, I urge you to read this article. There are three cold-hard facts you should know about before you go out and make your next purchase.
In fact, the most important thin you should consider in your facial moisturizers are the ingredients. Most people don't seem to realize that the vast majority of the skin care products on the market are formulated using primarily chemical agents as ingredients, instead of the safe, all natural ingredients. These chemicals can cause you to develop some serious health problems (some ingredients have been linked to cancers and have been banned by the EU).
Cold Hard Fact #1: Scented Facial Moisturizers Are Worthless (And Even Harmful)
Even the aromas in facial cream, which as stated are huge selling points, can cause you to have a myriad of reactions. In recent years dermatologists have complained about the chemical agents that are used to engineer scent in cosmetics products. They claim that these chemicals are responsible for the majority of the allergic reactions they treat every year.
But the chemical agents used in facial moisturizers to "smell pretty" are the least of your ingredient worries. There are additives and preservatives in most of the skin care products on the market that have been scientifically proven to be toxic to humans. It is amazing to me that the FDA has not yet been able to ban these ingredients from use.
Cold Hard Fact #2: Ingredients Are King
The ingredients that can be typically found in facial cream have been shown to be neurotoxins, organ toxins, and carcinogens. Of course, not all of the chemical agents that these corporations use have turned out to be dangerous, but most of those tested so far have. Logic tells me that I would be far better off choosing skin care products that are safe for me to use in the long-term.
This means that you would be well-served to seek out the few facial moisturizers on the market that contain strictly all natural ingredients. Not only will your long-term health improve, but years of testing and tweaking has made these natural ingredients as effective (if not more) than their chemical imposters.
The formula for facial cream is simple. Bad ingredients = bad facial moisturizers. Period.
Cold Hard Fact #3: The Smaller the Company, the Better the Product
Larger cosmetic companies spend a majority of their budget on marketing. Did you catch the significance there? They spend MOST of their budget on marketing - not research and development. Part of the reasons these companies use chemical and petroleum-based products in their skin care line is because it's so CHEAP to do so.
Smaller companies realize they can't fight the marketing battle. So they have to spend every dime in researching and developing better products. That is why nearly all the natural skin care manufacturers are smaller companies that build their customer base through word-of-mouth advertising (without the high-cost celebrities).
The company I use for my facial cream is one of those innovative pioneer companies. They have developed a facial cream that naturally increases the amount of collagen, elastin, and hyaluronic acid that your skin has. By increasing the production of these three structural tissues, your skin begins to replenish and renew itself.
Feed your skin with facial moisturizers containing all natural ingredients, and be rewarded you with younger, smoother, happier skin. Those all-natural companies are out there. Make it a mission to uncover them and give their products a try. Your starved skin will rejoice, I promise.
Naturally, if you're too busy for "skin research", feel free to browse through what I've uncovered over the years in the world of natural skin care. You can follow my journey toward naturally perfect skin at my website linked below.
About the Author
Ranae Pritchard is passionate about balancing "effectiveness" and "good for you" in skin care products. She believes beauty is much more than just skin deep. What you put on your skin is just as important as what you put in your mouth.
There are healthy and natural remedies to even the worst skin issues. The key is in the ingredients. Do you choose plant oils and extracts with proven clinical histories? Or chemical by-products that have been linked to cancers? The difference could be a long lifetime of glowing skin.
Learn more about how to choose good-for-you (and effective) skin care products on her website, "http://www.naturally-perfect-skin.com".
The Effect of Formulation on the Quality of Film Coated Tablets
By: Marina Levina and Charles R. Cunningham
Tablets are by far the most popular dosage form when administering drugs to patients, and a large proportion of the tablets produced around the world are film coated. Coating is applied for a variety of reasons such as aesthetic appearance; identification and branding; taste or odor masking; enhanced mechanical strength; and protection from moisture, light and/or air.
With the current awareness of health, safety and environmental problems, aqueous film coating is a process that is routinely employed in the preparation of pharmaceutical solid dosage forms. The success of this process is determined by three factors: formulation of the coating system, coating process parameters and tablet core. During the last 20 years, there has been significant research into coating formulations and processes. In focusing on these areas, less attention has been paid to issues that relate to the preparation of a suitable tablet or substrate. This article will highlight the importance of pharmaceutical formulation on the quality of a film coated tablet.
Tablet Formulation
The formulation of a robust tablet has to be considered in terms of:
- The ability of the core to withstand the mechanical stress of the process.
- Maximized adhesion of the coating to the tablet surface, especially when a logo is present.
- A smooth film coat with uniform thickness.
- The stability of the final coated dosage form on storage.
Tablet Mechanical Strength and Friability
The tablets being coated and the applied coating are constantly subjected to mechanical stress. Tablet breakage and surface erosion are typically seen when the mechanical strength and friability of the tablet core are inadequate. The problem can worsen during scale-up because of the increased weight of the tablets charged into the coating pan. This situation may occur after product approval, because the use of ever-increasing pan sizes is not uncommon as product sales increase. Therefore, any product that is performing poorly with respect to mechanical strength should not even be exposed to the scale-up process.
It is extremely difficult to create generalized guidelines defining the physical attributes of a robust tablet that is acceptable for use in a coating process because so much depends on the materials that are being used. Tablets with relatively low breaking force values should be dealt with much more carefully if they are to be coated, particularly during scale-up. Large tablets, such as multivitamin cores, may need to have greater mechanical strength values compared with smaller tablets.
A measure of equal or perhaps greater importance in terms of tablet robustness is friability. This test more accurately reflects the stresses that tablets will encounter when tumbling into a coating pan. Tablets to be film coated should have a maximum friability value of 0.3% and preferably less then 0.1%. This guideline should be adhered to regardless of tablet size or shape.
Drug and excipient particle characteristics can also have a significant affect on the success of film coating. Variations in coating thickness may present a serious problem when the properties of the film are dependent on its thinnest part, particularly in the case of modified drug release coatings.
Adhesion of Film Coating to the Tablet Core
Good adhesion between a polymeric film and a tablet is a fundamental requirement to guarantee a good bond between the coating and surface of the core as the tablets tumble in the coating pan, and to maintain the clarity of logos. For the formation of an adequate and adhesive film coat, the atomized droplets have to spread completely over the surface of the core – and to a certain degree penetrate into a substrate. Some of the materials used in tablet formations, however, may interfere with the intermolecular bonding at the film-substrate interface and hinder adhesion of the film to the core.
Lubricants are added to tablet formulations to minimize both die-wall friction and punch adhesion. Both of these requirements necessitate that the lubricants function at the tablet surface, precisely where they are counterproductive in the adhesion process considering the inherent hydrophobicity of lubricants, such as metal stearates.
No excipient used in such small quantities can have as detrimental effect on tablet quality than magnesium stearate. Magnesium stearate, although a very effective lubricant, can reduce the mechanical strength of the cores, decrease film adhesion and slow drug dissolution. Therefore, the quantity of magnesium stearate used in a tablet formulation should be minimized. Self-lubricating products such as Starch 1500 can also be used to reduce the need for significant lubricant addition.
Conclusion
Many of the ingredients chosen in initial tablet formulation development can have a significant impact on aqueous film coating quality. They may affect the physical, mechanical, adhesive, drug-release and stability properties of the coated dosage form.
Decisions as to the ultimate appearance of the tablet are often left until later stages of development and can impact coating quality. To ensure success in the film coating process, formulation along with the design of the tablet should be considered early in the development.
About Colorcon®
Colorcon® is a world leader in the development, supply and technical support of formulated coatings and excipients for the pharmaceutical industry. With Colorcon as their pharmaceutical product development partner, companies produce cost effective, high quality products with superior performance and appearance. To learn more, please visit http://www.colorcon.com/.
About the Author
About the Authors
Marina Levina is the global technical manager, MR applications at Colorcon Ltd., UK. Charles R. Cunningham is the pharmaceutical technical services manager, at Colorcon, USA.
